PhD candidate: Atomic force microscopyAdvanced methods in atomic force microscopy allow us to image and to characterize (bio)molecules with very high resolution. In this PhD project we shall push the limits of AFM further to characterize mechanical and electrical properties of DNA protein complexes. Resolution and sensitivity of new multi-frequency techniques shall be explored. The successful candidate has a background (MSc or equiv) in materials sciences, physics or engineering and a strong interest in nanoscience and biophysics. Start: Oct. 2010 PostDoc: MicrofluidicsMicrofluidic systems with functional surfaces are valuable tools for biomedical research. Highly specialized devices allow for the investigation of various biological processes in vitro. The adhesion of blood platelets in an artery is one example for a biological process that occurs in a liquid flow. The activation and adhesion of blood platelets to surfaces is an important step in the healing of an injured blood vessel. In order to investigate cell adhesion under flow conditions in vitro we develop a microfluidic system which mimics flow conditions and surface functionality of an blood vessel. The microfluidic device mimics different configurations of the vascular system: Straight channels induce a uniform and laminar flow with high shear stress, wheres the bifurcations (low stress) or curved geometries change the flow pattern. In prticular, the surface functionality needs to be defined locally. The successful candidate has a background (MSc or equiv) in materials sciences, physics or engineering. The candidate has experience in microdevice fabrication or microfluidics. Fluent English and proven writing skills together with a strong interest for biological systems allows the candidate to communicate with partners in biology or medicine. The position (TVL-E13) is available for 1 year and can be extended. Start: Jan 2011
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